CNNC self-developed injectable BNCT boron drug enters clinical trial stage

Forum Contacts RSS		RUSSIAN

CNNC, PUBLISHED 15.01.2026

The injectable borofalan (10B), independently developed by CNNC Headway, a subsidiary of China Isotope & Radiation Corporation (CIRC) under the China National Nuclear Corporation (CNNC), has received the "Drug Clinical Trial Approval Notice" from the National Medical Products Administration (NMPA) of China.

This marks the official entry of the drug into Phase I clinical trials.

On January 9, the collaborative clinical project for the Boron Neutron Capture Therapy (BNCT) drug-device combination was officially launched by CNNC Headway, Lanzhou University, Fujian RAYSCO Medical Technology Co Ltd, and Fujian Medical University Union Hospital.

BNCT is a novel, precisely targeted radiotherapy method for cancer cells. It relies on the specific affinity of boron-10 compounds for cancer cells.

After the drug accumulates in the tumor site, neutron beam irradiation triggers a boron neutron capture nuclear reaction, thereby precisely destroying tumor cells while maximizing protection for surrounding normal tissues.

BNCT has emerged as a highly promising frontier direction in the field of tumor therapy.

The launch of this project is a vivid demonstration of CIRC and its subsidiary CNNC Headway's practice of enterprise-local government collaboration and their promotion of deep integration among industry, academia, and research.

It leverages the core advantages of all parties in the BNCT field to form a powerful synergy. CNNC Headway has deep expertise in the nuclear medicine sector.

The approved injectable borofalan (10B) will provide the core boron drug for the BNCT treatment system, accelerating the industrial application of BNCT.

Topics: Asia, China, Nuclear medicine

Other news:

Tianwan Nuclear Power Unit 7 completes hot functional test

Hot functional test is conducted prior to fuel loading.

Unit No. 2 has been permanently shut down at the Bilibino NPP

Units No.3 and No.4 will be shut down till end of year.

Reactor Vessel Installed at El-Dabaa NPP Power Unit 1 in Egypt

Rafael Grossi, Director General of the IAEA addressed the participants in video message.

Hero of the day

Rosatom starts modernization of its third uranium enrichment plant

In Seversk, Tomsk Region, the first block of high-performance 9+ generation gas centrifuges has been launched at the Isotope Separation Plant of the Siberian Chemical Combine (an enterprise of Rosatom's Nuclear Fuel Division).

INTERVIEW

Rosatom
On November 18, in St. Petersburg, President of Russia Vladimir Putin took part via videoconference in the keel-laying ceremony for the Project 22220 sixth serial-produced universal nuclear-powered icebreaker Stalingrad.

OPINION

CNNC
On July 12, China National Nuclear Corporation (CNNC) achieved a milestone at the "National No 1 Uranium" demonstration project in Ordos, Inner Mongolia autonomous region, producing its first barrel of uranium product.